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June 2001
1) Community News Hi All- Enjoy your summer!
Hannah 2) You Should Continue Breastfeeding (1) (Drugs and Breastfeeding)
Over the years, far too many women have been wrongly told they had to stop breastfeeding.
The decision about continuing breastfeeding when the mother takes a drug, for example, is far
more involved than whether the baby will get any in the milk. It also involves taking into
consideration the risks of not breastfeeding, for the mother, the baby and the family, as well
as society. And there are plenty of risks in not breastfeeding, so the question essentially
boils down to: Does the addition of a small amount of medication to the mother’s milk make
breastfeeding more hazardous than formula feeding? The answer is almost always: Almost never.
Breastfeeding with a little drug in the milk is almost always safer. In other words, being
careful means continuing breastfeeding, not stopping.
Remember that stopping breastfeeding for a week may result in permanent weaning since the
baby may then not take the breast again. On the other hand, it should be taken into consideration
that some babies may refuse to take the bottle completely, so that the advice to stop is not only
wrong, but often impractical as well. On top of that it is easy to advise the mother to pump her
milk while the baby is not breastfeeding, but this is not always easy in practice and the mother
may end up painfully engorged.
Breastfeeding and Maternal Medication
Most drugs appear in the milk, but usually only in tiny amounts. Although a very few drugs may
still cause problems for infants even in tiny doses, this is not the case for the vast majority.
Nursing mothers who are told they must stop breastfeeding because of a certain drug should ask the
physician to make sure of this by checking with reliable sources and/or prescribing an alternative
safe medication. In this day and age, it is rarely a problem to find a safe alternative. If the
prescribing physician is not flexible, the mother should seek another opinion, but not stop
breastfeeding.
Why do most drugs appear in the milk in only small amounts? Because what gets into the milk
depends on the concentration in the mother’s blood and the concentration in the mother’s blood
is often measured in micro- or even nano-grams per millilitre (millionths or billionths of a
gram), whereas the mother takes the drug in milligrams (thousandths of grams) or even grams.
Furthermore, not all the drug in the mother’s blood can get into the milk. Only the drug that
is not attached to protein in the mother’s blood can get into the milk. Many drugs are almost
completely attached to protein in the mother’s blood. Thus, the baby is not getting amounts of
drug similar to the mother’s intake, but almost always, much much less on a weight basis. For
example, in one study with paroxetine (Paxil), the baby got less than 0.3% of the drug for each
kilogram of his weight than the mother did (the mother got over 300 micrograms per kg per day,
whereas the baby got about 1 microgram per kg per day).
Most drugs are safe if:
They are commonly prescribed for infants. The amount the baby would get through the milk is
much less than he would get if given directly. The following are a few commonly used drugs considered safe during breastfeeding:
Acetaminophen (Tylenol, Tempra), alcohol (in reasonable amounts), aspirin (in usual doses, for
short periods). Most antiepileptic medications, most antihypertensive medications, tetracycline,
codeine, nonsteroidal antiinflammatory medications (such as ibuprofin), prednisone, thyroxin,
propylthiourocil (PTU), warfarin, tricyclic antidepressants, sertraline (Zoloft), paroxetine
(Paxil), other antidepressants, metronidazole (Flagyl), omperazole (Losec), Nix, Kwellada.
Note: Though generally safe, fluoxetine (Prozac) has a very long half life (stays in the body
for a long time). Thus, a baby born to a mother on this drug during the pregnancy, will have
large amounts in his body, and even the small amount added during breastfeeding may result in
significant accumulation and side effects. These are rare, but have happened. There are two
options that you might consider:
Stop the fluoxetine (Prozac) for the last 4 to 8 weeks of your pregnancy. In this way, you
will eliminate the drug from your body and so will the baby. Once the baby is born, he will be
free of drug and the small amounts in the milk will not usually cause problems and you can
restart the fluoxetine (Prozac).
If it is not possible to stop fluoxetine (Prozac) during your pregnancy, consider changing to
another drug which does not get into the milk in significant amounts once the baby is born.
Two good choices are sertraline (Zoloft) and paroxetine (Paxil).
Medications applied to the skin, inhaled (for example, drugs for asthma) or applied to the
eyes or nose are almost always safe for breastfeeding.
Drugs for local or regional anaesthesia are not absorbed from the baby’s stomach and are safe.
Drugs for general anaesthesia will get into the milk in only tiny amounts (like all drugs) and
are extremely unlikely to cause any effects on your baby. They usually have very short half lives
and are eliminated extremely rapidly from your body. You can breastfeed as soon as you are awake
and up to it.
Immunizations given to the mother do not require her to stop breastfeeding. On the contrary,
the immunization will help the baby develop immunity to that immunization, if anything gets into
the milk. In fact, most of the time nothing does get into the milk, except, possibly some of the
live virus immunizations, such as German Measles. And that’s good, not bad.
X-rays and scans. Ordinary X-rays do not require a mother to stop breastfeeding even when used
with contrast (example, intravenous pyelogram). The reason is that the material does not get into
the milk, and even if it did it would not be absorbed by the baby. The same is true for CT scans
and MRI scans. You do not have to stop for even a second.
What about radioactive scans?
We do not want babies to get radioactivity, but we rarely hesitate to do radioactive scans on
them. When a mother gets a lung scan, or lymphangiogram with radioactive material, or a bone scan,
it is usually done with technetium (though other materials are possible). Technetium has a half
life (the length of time it takes for ½ of all the drug to leave the body) of 6 hours, which means
that after 5 half lives it will be gone from the mother’s body. Thus, 30 hours after injection all
of it will be gone and the mother can nurse her baby without concern about his getting radiation.
But does all the radioactivity need be gone? After 12 hours, 75% of the technetium is gone, and
the concentration in the milk very low. I think that after most radioactive scans, the mother can
continue breastfeeding, but if she and her physician are truly concerned, waiting 2 half lives is
enough, for a material such as technetium. Note that if the mother is getting the scan during the
first few days after the baby’s birth, the baby will get much less because the baby gets much
less milk during this time. During this early period, I believe no interruption of breastfeeding
is necessary or desirable. Colostrum is desirable for the baby.
If you decide that interruption of breastfeeding is the best course to follow, then express
milk for several days in advance (if you have advance warning about the test). Only occasionally
is a radioactive scan that urgent that it cannot be delayed for a few days.
Thyroid scans are different. Radioactive iodine is concentrated in milk and will be ingested
by the baby and it will go to his thyroid where it will stay for a long time. This is definitely
of concern. So, the mother will have to stop breastfeeding? No, because often the test does not
need to be done. Differentiating postpartum thyroiditis from Graves’ Disease
(the most common reason for doing the scan in nursing mothers) does not require a thyroid scan.
Get more information from the clinic. If a scan needs to be done, it is possible to do a thyroid
scan with technetium.
Questions? (416) 813-5757 (option 3) or newman@globalserve.net
January 2000 3) Support, Links and Lists for Work-At-Home-Moms Working at home and raising your children is quite challenging! Dedication and support for
both working and mothering greatly helps. Whether you are currently working at home or thinking
about it here are some great resources for you:
LINKS
BOOKS
*Motherhood at the Crossroads : Meeting the Challenge of a Changing Role *Diary of a Small Business Owner : A Personal Account of How I Build a Profitable Business *The Stay-At-Home Mom's Guide to Making Money : How to Create the Business That's Right for You Using the Skills and Interests You Already Have *101 Best Home Based Businesses for Women *101 Best Extra Income Opportunities : Special Money-Making Ideas for Women Who Run Out of Money Before They Run Out of Month *How to Raise a Family & A Career Under One Roof : A Personal Guide to Home Business for Parents" *Mompreneurs : A Mother's Practical Step-By-Step Guide to Work-At-Home Success LISTS
Here are just a few discussion/support lists. A great way to find more is to go to
ONELIST.com and do a search for "work at home". You will then come up with hundreds to look
over!
~Work At Home ASAP: www.onelist.com/group/work-at-home-ASAP Copyright by J.E.D. Publishing
Reprinted from Attached! Newsletter Spring 2000 Breastfeeding-
"Ouch Pinching!" Nighttime Parenting-
"Baby sleep through night when cosleeping/breastfeeding?" Diapering-
"Ideas on diaper storage, Anyone?" Join in the discussions at the Babies Community Message Boards! |